Urinary Pathogen ID/AMR Enrichment Kit

The Urinary Pathogen ID/AMR Panel (UPIP) is a next-generation sequencing (NGS) research panel that enables detection and quantification of over 170 uropathogens responsible for urinary tract infections (UTIs) and co-infections and covers more than 3700 markers and their alleles associated with antimicrobial resistance (AMR). 

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Key features
  • Delivers simultaneous detection of 120+ bacteria, 35 viruses, 14 fungi, 4 parasites, and 27 sexually transmitted pathogen plus associated AMR alleles
  • Enriches uropathogen target regions from a range of host and environmental samples
  • Detects less common, challenging-to-grow, and frequently missed uropathogens
  • Outperforms shotgun metagenomics and conventional urine culture methods
Specifications
Properties
Value
Properties:
Assay time
Value:
< 9 hr library prep and enrichment time
Properties:
Automation capability
Value:
Liquid handling robot(s)
Properties:
Hands-on time
Value:
< 2 hr library prep and enrichment time
Properties:
Input quantity
Value:
Based on volume (not concentration dependent)
Properties:
Instruments
Value:
MiSeq System, NextSeq 550 System, NextSeq 2000 System, NextSeq 1000 System, MiSeqDx in Research Mode, MiniSeq System, NextSeq 550Dx in Research Mode, MiSeq i100 System, MiSeq i100 Plus System
Properties:
Mechanism of action
Value:
On-bead tagmentation followed by a single hybridization step
Properties:
Method
Value:
Targeted DNA sequencing, Target enrichment
Properties:
Multiplexing
Value:
Up to 384 samples in a single run with unique dual indexes
Properties:
Nucleic acid type
Value:
DNA
Properties:
Sample type details
Value:
DNA extracted from human urinary clinical research samples and other surveillance related samples such as wastewater
Properties:
Specialized sample types
Value:
Not FFPE-compatible
Properties:
Species category
Value:
Other, Human, Virus, Bacteria
Properties:
Technology
Value:
Sequencing

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